diff --git a/CMakeLists.txt b/CMakeLists.txt
index 856400ff0..2a81d698a 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -60,7 +60,6 @@ option(MINITRACE "Enable Chrome tracing using the modified minitrace library" OF
 
 option(DEV_BRANCH "Development branch" OFF)
 CMAKE_DEPENDENT_OPTION(AMD_K5 "AMD K5" ON "DEV_BRANCH" OFF)
-CMAKE_DEPENDENT_OPTION(CL5422 "Cirrus Logic CL-GD 5402/5420/5422" ON "DEV_BRANCH" OFF)
 CMAKE_DEPENDENT_OPTION(CYRIX_6X86 "Cyrix 6x86" ON "DEV_BRANCH" OFF)
 CMAKE_DEPENDENT_OPTION(GUSMAX "Gravis UltraSound MAX" ON "DEV_BRANCH" OFF)
 CMAKE_DEPENDENT_OPTION(HEDAKA "Hedaka HED-919" ON "DEV_BRANCH" OFF)
@@ -69,19 +68,15 @@ CMAKE_DEPENDENT_OPTION(MGA "Matrox Mystique graphics adapters" ON "DEV_BRANCH" O
 CMAKE_DEPENDENT_OPTION(NO_SIO "Machines without emulated Super I/O chips" ON "DEV_BRANCH" OFF)
 CMAKE_DEPENDENT_OPTION(OPEN_AT "OpenAT" ON "DEV_BRANCH" OFF)
 CMAKE_DEPENDENT_OPTION(PAS16 "Pro Audio Spectrum 16" OFF "DEV_BRANCH" OFF)
-CMAKE_DEPENDENT_OPTION(PS1M2133 "IBM PS/1 model 2133" ON "DEV_BRANCH" OFF)
 CMAKE_DEPENDENT_OPTION(PS2M70T4 "IBM PS/2 model 70 (type 4)" ON "DEV_BRANCH" OFF)
 CMAKE_DEPENDENT_OPTION(S3TRIO3D2X "S3 Trio3D/2X" ON "DEV_BRANCH" OFF)
 CMAKE_DEPENDENT_OPTION(SIO_DETECT "Super I/O Detection Helper" ON "DEV_BRANCH" OFF)
-CMAKE_DEPENDENT_OPTION(STPC "STPC machines" ON "DEV_BRANCH" OFF)
-CMAKE_DEPENDENT_OPTION(M1489 "ALi M1489" ON "DEV_BRANCH" OFF)
 CMAKE_DEPENDENT_OPTION(M154X "ALi ALADDiN IV" ON "DEV_BRANCH" OFF)
 CMAKE_DEPENDENT_OPTION(M6117 "ALi M6117" ON "DEV_BRANCH" OFF)
 CMAKE_DEPENDENT_OPTION(VGAWONDER "ATI VGA Wonder (ATI-18800)" ON "DEV_BRANCH" OFF)
 CMAKE_DEPENDENT_OPTION(VNC "VNC renderer" ON "DEV_BRANCH" OFF)
 CMAKE_DEPENDENT_OPTION(XL24 "ATI VGA Wonder XL24 (ATI-28800-6)" ON "DEV_BRANCH" OFF)
 CMAKE_DEPENDENT_OPTION(VECT486VL "HP Vectra 486VL" ON "DEV_BRANCH" OFF)
-CMAKE_DEPENDENT_OPTION(DELLS4 "Dell Dimension XPS P60; Dell OptiPlex 560/L" ON "DEV_BRANCH" OFF)
 
 # HACK: Avoid a MSVC2019 compiler bug on ARM64 Debug builds
 if(MSVC_TOOLSET_VERSION GREATER_EQUAL 142 AND CMAKE_TARGET_ARCHITECTURES STREQUAL "armv8")
diff --git a/src/machine/CMakeLists.txt b/src/machine/CMakeLists.txt
index 16850c58d..360ba7697 100644
--- a/src/machine/CMakeLists.txt
+++ b/src/machine/CMakeLists.txt
@@ -44,10 +44,6 @@ if(OPEN_AT)
 	target_compile_definitions(mch PRIVATE USE_OPEN_AT)
 endif()
 
-if(PS1M2133)
-	target_compile_definitions(mch PRIVATE USE_PS1M2133)
-endif()
-
 if(PS2M70T4)
 	target_compile_definitions(mch PRIVATE USE_PS2M70T4)
 endif()
diff --git a/src/win/Makefile.mingw b/src/win/Makefile.mingw
index 4546f4af4..e9d4abeea 100644
--- a/src/win/Makefile.mingw
+++ b/src/win/Makefile.mingw
@@ -36,9 +36,6 @@ ifeq ($(DEV_BUILD), y)
  ifndef AMD_K5
   AMD_K5	:= y
  endif
- ifndef CL5422
-  CL5422	:= y
- endif
  ifndef CYRIX_6X86
   CYRIX_6X86	:= y
  endif
@@ -69,9 +66,6 @@ ifeq ($(DEV_BUILD), y)
  ifndef PAS16
   PAS16		:= n
  endif
- ifndef PS1M2133
-  PS1M2133	:= y
- endif
  ifndef PS2M70T4
   PS2M70T4	:= y
  endif
@@ -112,9 +106,6 @@ else
  ifndef AMD_K5
   AMD_K5	:= n
  endif
- ifndef CL5422
-  CL5422	:= n
- endif
  ifndef CYRIX_6X86
   CYRIX_6X86	:= n
  endif
@@ -145,9 +136,6 @@ else
  ifndef PAS16
   PAS16		:= n
  endif
- ifndef PS1M2133
-  PS1M2133	:= n
- endif
  ifndef PS2M70T4
   PS2M70T4	:= n
  endif
@@ -544,10 +532,6 @@ OPTS		+= -DUSE_PAS16
 DEVBROBJ	+= snd_pas16.o
 endif
 
-ifeq ($(PS1M2133), y)
-OPTS		+= -DUSE_PS1M2133
-endif
-
 ifeq ($(PS2M70T4), y)
 OPTS		+= -DUSE_PS2M70T4
 endif